Manifesto has formulated a new supplement called Serene which has been designed to bring a moment of calm to women ‘doing it all’, especially during the menopause.
The brand says the launch comes at a time when more women than ever are searching for solutions to their hormonal health, citing that searches for ‘menopause and anxiety’ rose by over 70% in April – a reflection of how many women are navigating hormonal shifts and stress.
“It’s about offering women real support: something gentle, effective and beautiful to return to every day”
Described as being powerful yet gentle, the daily gummy combines ingredients that are carefully selected to support stress relief, hormone regulation, sleep quality and emotional wellbeing. The blend comprises:
- Clinically studied Ashwagandha KSM-66 helps reduce stress and anxiety
- Vitamins B6 and B12 support the nervous system and hormone balance, reducing symptoms of depression, irritability and tiredness in pre- and post-menopausal women
- A synergistic combination of vegan vitamin D (from Icelandic lichen), Ashwagandha KSM-66 and vitamin B6 boosts mood and enhances memory
- Calming chamomile and lemon balm extracts promote deeper, more restful sleep
- Vitamin B6 and jujube seed extract support a healthy immune and nervous system.
“Women are under enormous pressure to carry everything — their work, their families, their health — all while navigating the emotional waves of hormonal change, which is stressful,” comments brand founder and beauty-industry veteran Anna Marcovici, who sees Serene as more than a supplement, ‘it’s a daily act of self-care’.
“I created Serene because I know that weight too well. It’s about offering women real support: something gentle, effective and beautiful to return to every day.”
With compostable sachets and a reusable tin, Serene is designed to fit easily into the rhythms of modern life as ‘a new kind of supplement for a new kind of self-care’.



